AMSBIO Announces ClioCell™, a New Device for the Removal of Dying and Dead Cells

27 Mar 2014
Sarah Thomas
Associate Editor

Product news

AMSBIO announces ClioCell™ - an ex-vivo device for removal of dying and dead cells, improving viability and quality of cell populations and their subsequent productivity.

The system comprises super-paramagnetic nanoparticles which have been coupled with proprietary elements that bind to dead and dying cells and cell debris. The resultant product selectively initiates dead-cell removal, emulating dead-cell clearance mechanisms which operate in-vivo to keep tissues functioning optimally. This technology is step-changing, providing new opportunities to optimize cell growth, culture and storage.

ClioCell™ has a broad array of uses, spanning a number of diverse academic and industrial applications. The ability to selectively remove inhibitory or toxic dead cells using a simple and rapid procedure results in radically improved cell populations; specifically, with regard to viability antibody/protein yield and consequent functional efficacy. ClioCell™ has been evaluated by several leading independent commercial and academic research institutions working on cell culture projects. It has been successfully tested on many cell types, both human and mammalian. ClioCell™ can be manufactured to cGMP grade and our team has experience of many cell types, pre and post thaw applications and "Big Pharma" project work.

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Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Cell ViabilityCell viability assays assess the health of cells and their ability to proliferate. These tests are crucial in drug development, toxicity testing, and cell-based research. Common methods for assessing viability include MTT, live/dead assays, and flow cytometry. Browse our peer-reviewed product directory to find the best tools for cell viability assays, compare products, check reviews, and get pricing directly from manufacturers.
AMSBIO Announces ClioCell™, a New Device for the Removal of Dying and Dead Cells