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Amnis Introduces New FlowSight Imaging Flow Cytometer

Merck
13 Jun 2011
bridget bridget
Laboratory Director

Product news

Amnis Corporation, a manufacturer of advanced cell imaging systems, today announced the launch of the new FlowSight imaging flow cytometer.

The FlowSight is a compact and affordable 12-channel flow cytometer with unrivalled fluorescence sensitivity and the breakthrough ability to produce imagery of every cell. The modular FlowSight can be upgraded in the factory or the field with up to four lasers, a 96-well AutoSampler, and a Quantitative Imaging package, thereby providing the capabilities and flexibility to meet the needs of a broad range of users.

“With 12 detection channels, visual verification of every cell, and affordable pricing, the FlowSight is designed to serve the needs of beginners and expert flow cytometrists alike,” said David Basiji, Ph.D., Amnis’ Chief Executive Officer. Basiji added, “The FlowSight complements Amnis' flagship ImageStreamX imaging flow cytometer, a high resolution microscope for cells in fluid suspension that enables numerous image-based assays in rare sub-populations.”

“The FlowSight is based on the proven ImageStreamX architecture and shares its remarkable fluorescence sensitivity, exceeding that of high-end conventional flow cytometers by five-fold or more,” remarked William Ortyn, Amnis’ President and COO. “With the FlowSight, Amnis is fulfilling its promise to bring cell imaging to the larger flow cytometry market,” added Ortyn.

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Flow Cytometry / Cell CountingFlow cytometers are used to count, sort and examine multiple characteristics of cells. Other cell analysis equipment includes image cytometers, cell counters, fluorescence-activated cell sorters (FACS), magnetic-activated cell sorters (MACS), and a range of flow cytometry assay kits. Flow cytometers can reveal information on cell viability, cell proliferation, apoptosis and cell cycle progression, as well as identify cell populations and intracellular or cell-surface molecules. Additionally, some flow cytometers, known as FACS, have an additional sorting function after analysis. Cell counters and image cytometers count live and dead cell populations and can also conduct cell proliferation assays. Find the best flow cytometers, cell counters and cell sorters in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Protein PurificationProtein purification is a vital step in drug discovery, therapeutics, biotech and life science research. The purification process typically involves subcellular or membrane protein extraction with cell lysis kits, separation of proteins from cell debris by filtration or spin columns, and the isolation of proteins of interest from other proteins and impurities with affinity purification (including fusion protein tags and antibody binding proteins A, G and L), immunoprecipitation or chromatographic methods, such as ion exchange, size exclusion and immobilized metal affinity chromatography. All purification methods come in multiple formats for your laboratory needs, including agarose or magnetic beads, resins, columns and filter plates. Find the best protein purification equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.

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