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All antibodies are NOT created equal: Comprehensive profiling of SARS-CoV-2 antibodies

SelectScience
7 Sept 2020
Edward Carter
Publishing / Media

Expert insights

Prof. Tuomas Knowles, Founder and Chief Scientific Officer at Fluidic Analytics

Detecting antibodies that confer effective immunity is crucially important to understand a patient’s immune response to SARS-CoV-2. In particular, the ability to quantify the virus-neutralizing capacity of the immune system is key to support the development of suitable vaccines and antibody-based treatments such as convalescent plasma therapies.

This talk outlines our efforts in assessing the immune response in COVID-19 patients by use of a novel microfluidic in-solution immunoassay platform. With this new approach, we were able to comprehensively profile SARS-CoV-2 antibodies directly in minimally diluted serum of these patients.

Register here

During the event, Prof. Tuomas Knowles, Founder and Chief Scientific Officer at Fluidic Analytics, will be looking into:

  • Understand the drawbacks of standard immunoassays such as ELISA tests
  • Understand that affinity-based antibody profiling is key for a comprehensive understanding of the immune response against SARS-CoV-2
  • Learn about the ability to assess the immune response of COVID-19 patients directly in minimally diluted serum by use of our novel in-solution immunoassay platform
  • Understand how this technology can be leveraged by scientists in the fight against COVID-19

Certificate of attendance

All webinar participants can request a certificate of attendance, and a learning outcomes summary document for continuing education purposes.

This webinar will run on Friday, September 25, at:

  • 16:00 BST
  • 17:00 CEST
  • 11:00 EDT
  • 08:00 PDT

Register for this webinar here>>

SelectScience runs more than 10 webinars a month across various scientific topics, discover more of our upcoming webinars>>

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.ELISAEnzyme-linked immunosorbent assays (ELISA), also known as enzyme immunoassays (EIA), are used for the detection and quantification of proteins, peptides and antibodies in a sample. ELISA often comes in kit format, with pre-selected antibody pairs to detect specific proteins or biomarkers of diseases such as diabetes and obesity, or cardiovascular and neurological disorders. Detection is made possible with chemiluminescent, fluorescent or colorimetric substrates and detection instruments such as microplate / ELISA readers. Other kits available include: Enzyme-linked immunospot (ELISPOT) assays for the quantification of protein-producing cells and chemiluminescent immunoassays (CLIA) kits. Find the best ELISA kits and products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.CoronavirusCoronaviruses are a large family of viruses that can cause illnesses ranging from the common cold to more severe diseases like COVID-19. Research into the biology, transmission, and treatment of coronaviruses has become a global priority, particularly since the emergence of SARS-CoV-2. Understanding the virus�s structure and behavior is essential for developing vaccines, diagnostics, and antiviral treatments. Explore our peer-reviewed product directory to discover the latest research tools, diagnostic tests, vaccines, and treatments for coronavirus, compare products, read reviews, and receive pricing directly from manufacturers.

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