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Agilent Technologies and PureHoney Technologies to Develop New Applications for RapidFire/MS System

Agilent Technologies
2 Nov 2016
Emily Adam
Publishing / Media

Industry news

Agilent Technologies Inc. and PureHoney Technologies have announced a co-marketing agreement to develop new applications on the Agilent RapidFire 365 High-throughput Mass Spectrometry System.

Agilent acquired the RapidFire technology when it purchased BIOCIUS Life Sciences in 2011. PureHoney Technologies is a contract research organization founded in 2014 by the original developers of RapidFire MS instrumentation.

Agilent and PureHoney will work together to develop new applications for the Agilent RapidFire/MS System, and will independently create new workflows for pharma and biopharma research, as well as forensic toxicology and metabolomics analysis.

“Our partnership with PureHoney Technologies will enable both companies to synergistically enhance application offerings, providing scientists with a greater range of capabilities to enhance the depth and speed of pharmaceutical research,” said Monty Benefiel, Agilent vice president and general manager of the company’s Mass Spectrometry Division.

“Originally developed as a tool for label-free high-throughput screening over a decade ago, RapidFire/MS is now routinely used in applications ranging from ADME-Tox, proteomics metabolomics, clinical research to in vivo functional assays,” said Can Özbal, PureHoney Technologies president and CEO. “We are thrilled to be partnering with Agilent to develop the next generation of applications on this versatile platform.”

The Agilent RapidFire/MS system includes drug-screening technology that provides results 10 to 100 times faster than conventional screening methods. With more than 50 peer-reviewed journal articles, RapidFire/MS is widely accepted as the benchmark platform in high-throughput mass spectrometry. This ultra-high-throughput analysis dramatically increases productivity, providing faster results.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. High-Throughput ScreeningHigh-throughput screening (HTS) is an automated drug discovery technique for identification of active compounds against a compound library. Use HTS readers and integrated assay preparation / analysis workstations to screen your compounds. Identify active compounds against various HTS libraries, including membranes, proteins and peptides and HTS cell lines. Find the best high-throughput screening products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.MetabolomicsMetabolomics is the study of small metabolites (the intermediates and products of metabolism). It involves the identification and quantification of cellular metabolites using analytical technologies such as GC, HPLC, NMR, and LC/MS.High ThroughputHigh throughput experiments allow the simultaneous processing of several samples. This parallelization reduces the cost per experiment and increases reproducibility and output volume of data.BiopharmaceuticalsBiopharmaceuticals are proteins and other compounds (such as nucleic acids) produced by living organisms that have uses as therapeutics or for in vivo diagnostics. The most well known example of a biopharmaceutical product, and the first to be approved for therapeutic use, was recombinant human insulin.PharmaceuticalsPharmaceuticals are medicinal drugs used in healthcare to diagnose, prevent, cure and treat illnesses. Pharmaceuticals that are excreted after use appear in wastewater and can have detrimental effects on the environment.Forensic ToxicologyForensic toxicology is used to determine cause of death, drug use and contaminations. Toxicological evaluations are commonly used in analytical chemistry, clinical, life sciences and forensics.Drug Discovery & Development Screening

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Agilent Technologies and PureHoney Technologies to Develop New Applications for RapidFire/MS System