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Agilent showcases comprehensive cancer portfolio solutions at AACR 2023

Agilent Technologies

From cancer research to diagnostic solutions

17 Apr 2023
Lawrence Howes
Editorial Assistant

Industry news

Agilent Technologies Inc., will introduce its new cell analysis, genomics, digital pathology, and companion diagnostics solutions at the American Association for Cancer Research (AACR) Annual Meeting 2023 in Florida, USA.

Cancer is the second most common cause of death in the US, and the incidence continues to increase, with over 1.9 million new cancer cases expected to be diagnosed in 2023. An estimated 41 out of 100 men and 39 out of 100 women will potentially develop cancer during their lifetime.

A highlight at AACR will be the full commercial launch of the new Agilent SureSelect Cancer Comprehensive Genomic Profiling (CGP) assay, an NGS-based pan-cancer panel for somatic variant detection from solid tumors. This cancer CGP assay provides the ability to sequence DNA and RNA in parallel to detect key classes of somatic alterations.

Also announced is a strategic partnership between Agilent and PathAI to deliver AI-powered assay development solutions. Combining Agilent’s in vitro diagnostics workflow expertise with PathAI’s proprietary algorithm development platform will enable the integration of AI in CDx development, building intelligent solutions and assays with integrated AI algorithms from the outset. This builds on the announcement in March of an end-to-end solution for digital pathology that brings together products from Agilent, Visiopharm, Proscia®, and Hamamatsu Photonics K.K.

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Fragment Analyzer Systems

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The Agilent Fragment Analyzer systems are fluorescence-based capillary electrophoresis instruments for the accurate sizing, quantification, and qualification of nucleic acids (DNA and RNA).

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BiosensorsBiosensors are devices used to detect an analyte using biological molecules specific to the analyte coupled to a detector. Biosensor instruments may be photometric, typically using surface plasma resonance (SPR), electrochemical or QCM (quartz crystal microbalance) biosensors. Biosensors should be selective, portable, robust and sensitive and have a fast response time. Systems may be manual or automated and usually have associated software.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Next Generation SequencingNext-generation sequencing (NGS), also known as whole-genome sequencing, high-throughput sequencing and massive parallel sequencing, produces and analyses thousands to millions of nucleotide sequences at once. Sequencing systems operate via varying technologies depending on the manufacturer, including sequencing by synthesis, ligation, pyrosequencing, ion semiconductor and single-molecule real-time sequencing. For NGS, library preparation is paramount to successful sequencing. In this section, explore a range of library preparation kits, from targeted, amplicon-based or hybridization-based kits including epigenomic, transcriptomic and genomic workflows to fragmentation kits. Find the best next-generation sequencing products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cancer DiagnosticsThere are a wide variety of diagnostic tests for cancer available, and this range continues to expand as our knowledge of cancer improves. Current diagnostic methods include biopsy, imaging and blood tests for known biomarkers. New methods in research development include liquid biopsies and cancer breathalyzers.GenomicsGenomics is the study of genomes, focusing on the sequencing, analysis, and interpretation of genetic material. It is key in understanding genetic diseases, evolutionary biology, and personalized medicine. Techniques like next-generation sequencing (NGS) are commonly used in genomics research. Browse our peer-reviewed product directory to find the best genomics tools, compare products, check reviews, and get pricing directly from manufacturers.Assay DevelopmentThe process of proving an assay to be sensitive with respect to the target is known as assay development. The assay should be able to characterize novel compounds and measure the potency of these compounds against a validated biological target.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.

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