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Advanced PFAS/GenX LC-MS/MS workflows: Sample preparation and chromatography

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Register for this webinar to learn more about underlying chemistry considerations for sample preparation and chromatography of PFAS and GenX compounds

27 Mar 2020
Finn Price
Administrator / Office Personnel

Expert insights

Scott Krepich, Phenomenex
Scott Krepich, Phenomenex.

Per-and polyfluorinated alkyl substances (PFAS) continue to persist throughout the environment. High-profile water contamination incidents have raised public awareness, leading to even stricter protocols in US Unregulated Contaminant Monitoring Rules and European Drinking Water Directives, to name a few. In addition to this, there has been a growing interest in the examination of short-chained, branched isomers and PFAS replacement compounds, such as GenX.

In this upcoming webinar, HPLC/UHPLC expert Scott Krepich discusses the difficulties associated with analyzing trace levels of these ubiquitous compounds. Krepich will also review extraction solutions from multiple matrices, and how column chemistry contributions can help improve the analytics of shorter acids and GenX.

Register Now

In this webinar, you will cover:

  • How to apply particle morphology and column chemistry contributions for HPLC and UHPLC analyses of several PFAS workflows
  • The underlying chemistry contributions to apply QuEChERS techniques in solid soil, sediment, and food samples
  • Solid Phase Extraction solutions for EPA Methods 533, 537.1, and DOD QSM 5.3
  • How to reduce PFAS background for trace analysis

Who should attend?

  • Those working with PFAS/GenX analytes
  • Any scientist or analyst that wishes to learn more about the underlying HPLC/UHPLC column chemistry contributions for trace analysis
  • Any scientist or analyst that wishes to learn more about the underlying chemistry and workflow contributions for sample preparation considerations

The live webinar and Q&A session will take place on Tuesday, April 7, at:

  • 16:00 BST
  • 11:00 EDT
  • 08:00 PDT
  • 17:00 CEST

Register to watch the full webinar>>

SelectScience runs 3-4 webinars a month across various scientific topics, discover more of our upcoming webinars>>

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UHPLC and HPLCHigh performance liquid chromatography (HPLC) and ultra high performance liquid chromatography (UHPLC), also known as UPLC, are analytical techniques used to separate, identify and quantitate components of complex mixtures including biological samples such as proteins and lipids as well as chemical mixtures of pesticides, drugs and oils. Both techniques are liquid chromatographic methods but differ by operating pressures (HPLC < 6000 psi < UHPLC ). Components of HPLC and UHPLC systems include columns, detectors, pumps, autosamplers and column heaters. Explore a range of UHPLC and HPLC columns for your specific sample needs including reverse phase, normal phase, ion exchange, HILIC, ion exclusion and size exclusion columns. For more specialized HPLC, explore FPLC, countercurrent LC and simulated moving bed systems. Find the best UHPLC and HPLC equipment in our peer reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Sample PreparationSample preparation can improve the quality and speed of separation techniques. Products to assist sample preparation include filtration equipment, evaporators, membranes and sieves.EPA MethodsEPA methods are procedures approved by the U.S. Environmental Protection Agency for monitoring and analyzing environmental pollutants, including air, water, and soil samples. These methods are critical in ensuring public health and environmental safety. Explore EPA methods and tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.ChromatographyChromatography is a powerful technique used to separate and analyze components of mixtures based on their chemical properties. It is widely used in fields like biochemistry, pharmaceuticals, and environmental analysis. By exploiting differences in the interaction of substances with a stationary phase and a mobile phase, chromatography enables precise purification and quantification of compounds. Whether you're working with complex biological samples or industrial chemicals, chromatography is essential for obtaining high-quality results. Browse our peer-reviewed product directory to find the best chromatography systems, compare products, read customer reviews, and get pricing directly from manufacturers.Environmental ContaminationContaminants in the environment are harmful chemicals that are present in the air, land and water. These include pesticides, pharmaceuticals, persistent organic pollutants (POPs) and many more.Sample PreparationHPLCHigh-performance liquid chromatography (HPLC) is a technique for separating, identifying, and quantifying components in mixtures. It is widely used in chemical, pharmaceutical, and environmental analysis to ensure purity and identify unknown compounds. Explore the best HPLC systems in our peer-reviewed product directory; compare products, read reviews, and get pricing directly from manufacturers.Drinking Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).

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Advanced PFAS/GenX LC-MS/MS workflows: Sample preparation and chromatography