SelectScience
Join Free
Accelerating Science
NewsLife Sciences

Adeno-Associated Virus Services for Gene Delivery

AMSBIO

AMSBIO has introduced an expanded range of Adeno-associated virus (AAV) cloning and packaging services

23 Aug 2015
Lois Manton-O'Byrne, PhD
Executive Editor

Industry news

Adeno-associated viruses are single-stranded DNA viruses that can infect a broad range of cell types including dividing and non-dividing cells and are, therefore, widely used vehicles for gene delivery. Clinical trials have not only found AAV to be consistently safe and stable, but their vectors are capable of causing long-term expression in human cells. Therefore, AAV vectors have many advantages that many other vectors do not. To date, recombinant AAV (rAAV) vectors have been used in many clinical trials in gene therapy, and have achieved promising results from Phase 1 and Phase 2 trials.

AMSBIO offers the highest quality rAAV vectors and the most complete AAV Expression Systems that can be used to express shRNA, or human ORF. Through proprietary technology and innovative AAV vectors, AMSBIO is able to deliver reliable, reproducible, high purity, high titre viral stock every time. AMSBIO AAV vectors do not elicit significant immune response in vivo and therefore can be used for in vivo gene deliveries. Working with AMSBIO AAV vectors saves you time and increases your efficiency at a cost-effective price.

AMSBIO has also established a robust and professional AAV packaging service, ranging from the small crude scale to the large purified scale. Drawing upon its considerable experience and expertise AMSBIO is able to provide a platform that suits all your needs when it comes to combining scientific discovery and processing advancements in the field of gene therapy. With AMSBIO's production system, using AAV as a therapeutic vehicle for a broad range of diseases is now a simple task.

Links

AMSBIOCompany website

Tags

Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Clinical TrialsClinical Trials, an essential part of drug discovery process, assess the safety and effectiveness of a new medication or device in the pharmaceutical industry. Clinical Trials are a phased process (Phase 0, Phase I, Phase II, Phase III and Phase IV) which begins after initial preclinical testing.Clinical GeneticsMolecular Genetics covers the analysis of hereditary genetic disease and chromosomal abnormalities. Genetics can be analysed using DNA, RNA, and protein microarrays, PCR, RT PCR and DNA sequencing. Genetic equipment includes genetic workstations, thermal cyclers, cooling blocks and electrophoresis products. Diagnostic kits are used for DNA / RNA extraction and purification.Protein ExpressionProtein expression is the utilization of cell machinery for the synthesis of proteins and has become a critical tool in biotherapeutic, genomic, and proteomic research. Produce recombinant proteins with expression vectors in combination with a host cell suitable for high-level protein expression. For production of toxic proteins, consider cell-free expression vectors. Create and monitor post-translational modifications with protein modification kits. Find the best protein expression products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunology is the branch of medical science that covers the study of all aspects of the immune system of multicellular organisms.DNADeoxyribonucleic Acid (DNA) is the main component of chromosomes and the carrier of genetic information of living organisms. Find out here about PCR, NGS, ChIP-Seq, gel imaging, and many other techniques which can be used for the analysis of DNA.VirusesViruses are microscopic pathogens that require a host cell to replicate. Understanding their structure, replication cycle, and impact on the immune system is crucial in developing effective treatments, vaccines, and diagnostic methods. Research continues to focus on emerging viral diseases and antiviral drug discovery. Explore solutions for virus research, detection, and treatment in our peer-reviewed product directory; compare products, check customer reviews, and get pricing directly from manufacturers.ScreeningUsing robotics, data processing and control software, liquid handling devices and sensitive detectors, screening allows a researcher to quickly conduct millions of chemical, genetic or pharmacological tests.Gene TherapyGene therapy is a technique that modifies or replaces genes within an individual's cells to treat or prevent diseases. This approach holds potential for curing genetic disorders, cancers, and certain viral infections. Advances in gene editing technologies like CRISPR are driving the growth of gene therapy. Explore gene therapy tools and technologies in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.

Related articles