ACD/Labs Announces an Important Investment by Sanofi-Aventis for Production Facilities in Europe

17 Apr 2008
Greg Smith
Analyst / Analytical Chemist

Product news

Advanced Chemistry Development, Inc., (ACD/Labs), an industry leader in the development of software for NMR processing, prediction, and data management recently sold a suite of NMR software to one of the world’s leading pharmaceutical companies, Sanofi-Aventis, for use by five of its Process Development teams in production facilities in France, Germany, and Hungary.

NMR analysis is used in drug manufacturing to help identify impurities and degradants during filing and scale-up production process, and can also be used in a quality assurance capacity to help monitor the composition of the finished product.

Sanofi-Aventis needed a solution that would allow the analytical groups at some of its European Process Development sites to efficiently support internal clients with accurate NMR analysis. ACD/1D and 2D NMR Managers allow for off-instrument processing of analytical data and the ability to store results in a database searchable by structure as well as other parameters. ACD/Labs’ NMR Predictors provide predictions of 1D (1H, 13C, 15N, 19F, and 31P) and 2D NMR spectra, to help in the rapid interpretation and identification of potential impurities and degradants.

“With the help of ACD/Labs software tools we expect to be able to provide results to our internal clients, more quickly and accurately than in the past,” said Philippe Cleon, Head of Structural Analysis in Process Development (Neuville, France). “We were impressed with the ease of use of the software as well as the accuracy of the results we were able to obtain with these tools.”

“Before and during the implementation process, Sanofi-Aventis will receive full technical support from our staff.” said Yves Lorrain, Director of Sales, Chemcad. Chemcad is the distributor of ACD/Labs products for parts of Western Europe, including France, Belgium, Spain, The Netherlands, Sweden, Norway, Finland, and Denmark.

ACD/Labs has a range of NMR products to assist everyone—from the chemist to the expert spectroscopist.

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NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Process ChemistryProcess chemistry is an important stage of drug development for scaling-up drug production or chemical synthesis reactions. It is useful for optimizing economical and efficient drug production. Process chemistry uses reactors and pump systems as well as reagents, standards and buffers.
ACD/Labs Announces an Important Investment by Sanofi-Aventis for Production Facilities in Europe