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Abcam to Develop Bespoke Antibodies in New Partnership with Nanostring

Abcam plc

Partnership will develop conjugated FFPE IHC validated antibodies that are compatible with the GeoMx Digital Spatial Profiler

1 Apr 2019
Charlie Carter
Life Sciences Editor

Industry news

NanoString Technologies Inc., a provider of life science tools for translational research and molecular diagnostic products, today announced a commercial agreement with Abcam plc, a global innovator in life science reagents and tools, for the manufacture and sale of antibodies specifically for use with NanoString’s new GeoMx™ Digital Spatial Profiler (DSP).

"Researchers using our GeoMx DSP platform often want to customize their analysis. We have partnered with Abcam to facilitate access to their broad portfolio of high quality, validated antibodies to augment our off-the-shelf GeoMx Protein Panels. Abcam’s proven track record of antibody quality and performance was a key consideration in ensuring the success of our customer’s spatial profiling research", said Brad Gray, President and CEO of NanoString.

Under the terms of the agreement, Abcam will leverage its collection of over 6,000 recombinant monoclonal antibodies, validated for use with IHC in either fresh frozen or formalin-fixed paraffin-embedded (FFPE) tissue samples, to create bespoke antibody content for NanoString’s GeoMx DSP platform. This will enable GeoMx DSP users to more rapidly dissect and explore cellular interactions at a local level and facilitate discovery of novel biology.

"We are excited to be partnering with NanoString to support the GeoMx DSP users' ground-breaking research. Our recombinant monoclonal antibodies help ensure robust and quantitative spatial protein analysis of even the most challenging samples and may ultimately accelerate vital biomarker discoveries", said John Baker, SVP of Product Portfolio and Innovation at Abcam.

Discover the range of antibodies available from Abcam here.

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AntibodiesAntibodies are used in techniques such as confocal and fluorescence microscopy, flow cytometry, ELISA, ELISPOT, immunohistochemistry, western blotting and immunopreciptation. Select specific antigen reactivity, high specific affinity, low non-specific binding, monoclonal or polyclonal, primary or secondary antibodies and associated conjugates such as an enzyme or dye for visualization.BiomarkersBiomarkers are biological markers which can be measured and evaluated to indicate a biological state. The use of biomarkers in research and diagnosis can indicate a normal or disease state or drug response of cells / tissues. Biomarkers include genetic markers, cell surface markers such as antigens, antibodies or receptors and secreted molecules such as cytokines. An assay system is required for identification of biomarkers. :Monoclonal AntibodiesMonoclonal antibodies (mAbs) are lab-made molecules that can bind to specific antigens on cells, making them highly effective in treating cancers, autoimmune diseases, and infections. These targeted therapies are transforming the treatment landscape for many conditions. Browse our peer-reviewed product directory to find monoclonal antibodies for research and clinical applications; compare products, check reviews, and get pricing directly from manufacturers.Molecular DiagnosticsMolecular diagnostics use an individual’s genetic code and gene expression to diagnose and monitor diseases. The technique is used increasingly in the field of infectious diseases and oncology, as well as areas such as coagulation, HLA typing and pharmacogenomics. Molecular diagnostics plays a pivotal role in personalized medicine.Antibody ProductionAntibody production is essential for a wide range of applications in biochemistry and immunology. Ensuring high-quality monoclonal and polyclonal antibodies are produced is key. Explore antibody production tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.Engineered AntibodiesEngineered antibodies are modified to enhance specificity, stability, and functionality for therapeutic and diagnostic applications. These antibodies are central to immunotherapy and biomarker detection. Compare engineered antibody solutions in our directory to find top products and reviews.Biomarker DiscoveryClinical biomarkers refer to substances related to known medical conditions that can be accurately measured <i>in vitro</i>. Biomarkers can be used to diagnose presence of a disease and indicate disease severity. The discovery of new biomarkers is incredibly valuable in the field of diagnostics.

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Abcam to Develop Bespoke Antibodies in New Partnership with Nanostring