Abbott Introduces New Molecular Test to Aid in the Diagnosis of Tuberculosis

9 Oct 2014
Kathryn Rix
Administrator / Office Personnel

Industry news

Abbott announced it received CE mark approval for a new molecular diagnostic test for detection of Mycobacterium tuberculosis (MTB), the bacteria that causes tuberculosis (TB), which continues to be a major global public health threat.

The World Health Organization (WHO) estimates there were 8.6 million people who developed TB in 2012 and of these, an estimated 1.1 million people are also HIV-positive. People with compromised immune systems, such as those living with HIV-1, are more likely to develop tuberculosis.2 In high burden areas like Africa, where 75 percent of TB-HIV co-infections occur, Abbott is committed to helping reduce the global burden of infectious diseases and is working closely with health officials and medical teams to provide molecular diagnostic tests to help clinicians diagnose individuals with TB and to monitor response to HIV-1 therapy.

"Clinicians need access to reliable and highly sensitive molecular tests for TB and HIV to help curb transmission of these diseases," said Gavin Cloherty, Ph.D., director, global scientific affairs, infectious diseases, molecular diagnostics, Abbott. "TB is curable and with expanded access to molecular diagnostics technologies there is great potential to save lives in resource-limited areas."

Abbott's MTB test is performed on the automated m2000 molecular diagnostic testing system. The instrument can be adopted by laboratories of all sizes and offers efficiency by consolidating HIV-1 and MTB tests on the same platform. An MTB inactivation step is included with the MTB test procedure to reduce the risk of infection caused by airborne exposure to MTB during handling of sample material.

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MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.Plate ProcessingAutomated plate processing is used in microplate technologies for high-throughput, speed and efficiency. Plate processing systems include microplate handlers for moving plates, heat sealers, stackers and carousels for storage, retrieval and delivery, microplate washers and piercers. Useful features of plate processors include walk-away automation, compatibility and easy integration with microplate systems.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.TuberculosisHIV and AIDSBlood tests are the most common way to identify and monitor HIV and AIDS. Current methods include ELISA, Western blot, RT-PCR viral load and CD4/8 testing. Areas for development include point-of-care assays for use in developing countries, and self-testing ‘at home’ HIV kits.
Abbott Introduces New Molecular Test to Aid in the Diagnosis of Tuberculosis