AB SCIEX and Indigo Team Up to Market Clinical and Forensic Mass Spectrometry Solutions

19 Jan 2012
Sonia Nicholas
Managing Editor and Clinical Lead

Product news

AB SCIEX and Indigo BioSystems have announced an agreement to jointly market mass spectrometry solutions that streamline data acquisition and automate data review. The joint solutions have been designed to ensure high quality results in clinical research and forensic toxicology, as well as the pre-clinical and clinical trials of new drugs.

The agreement means that AB SCIEX will combine its industry-leading mass spectrometry platforms with Indigo BioSystem’s expert system software ASCENTTM , to simplify and accelerate the use of new-generation mass spectrometry technologies. ASCENTTM software has new-generation algorithms to simplify the use of mass spectrometry for scientists who are accustomed to easy-to-use lab analyzers. The software automates the processing and review of data generated by AB SCIEX systems, to provide the most accurate data possible with identification, quantitation and confirmation uniquely rolled up in a single workflow.

AB SCIEX is a global leader in mass spectrometry technologies. Its state-of-the-art LC/MS/MS (liquid chromatography/tandem mass spectrometry) has set a new standard in qualitative and quantitative analysis for clinical research and forensic toxicology laboratories as well as pharmaceutical companies and biomedical researchers in academia.

“Automation is an important step to accelerate the adoption of new-generation mass spectrometry for clinical research, forensics and clinical trials,” said Joe Anacleto, Vice President of Applied Markets and Clinical Research, AB SCIEX. “We are striving to make mass spectrometry as easy to use as possible for researchers analyzing steroids, pain panels, drugs of abuse and an expanding variety of substances. Our relationship with Indigo BioSystems allows us to bring LC/MS/MS solutions to researchers who may not ordinarily consider mass spectrometry but can now have the assurance of a simplified workflow while getting all the attractive benefits of LC/MS/MS technology.”

The combination of AB SCIEX’s and Indigo’s technologies will ensure the accuracy of results, speed up batch release and increase compliance with QC rules needed to ensure high quality.

“By embedding the knowledge of assay experts into the analysis software, we provide the foundation for smarter research laboratories,” said Indigo CEO Raul Zavaleta. “We are pleased to be partnering with the industry leader in LC/MS/MS to achieve this goal.”

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Data AnalysisData analysis hardware and software is available to make data processing straight-forward yet powerful. Data software can be used for math and stats, technical graphing and image analysis. In addition, software is available for specific data analysis of electrophoresis, densitometry, ELISA and DNA sequencing.Software PlatformsSoftware platforms are useful for various stages of laboratory experiments from data collection to data storage and processing. For instance lab software is available for system control, data management, data analysis and qualification / validation.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.Clinical MicrobiologyMicrobiology is the study of microorganisms including protists, prokaryotes, fungi, and, often, viruses. Microorganisms are a useful research tool as genetic vectors and, in immunology, for antibiotic susceptibility testing, cellular biology and genetics. Microorganisms commonly grow readily in incubators with microbial culture media; this can contain chromogenic supplements to differentiate between cell lines. Estimate your culture’s density of microorganisms with colony counters, or screen and select colonies for desirable clones with automated colony pickers. Additionally, equipment is available to monitor environments for the presence of microbes and identify with microbial identification instruments. Find the best microbiology products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Software Solution