AACC releases comprehensive guidelines on diabetes testing

In collaboration with the American Diabetes Association, the new guidelines are designed to improve patient care

23 Jul 2023
Lawrence Howes
Editorial Assistant

Industry news

AACC releases comprehensive guidelines on diabetes testing
ADLM (formerly AACC) collaborates with the American Diabetes Association to produce new diabetes guidelines

The American Association for Clinical Chemistry (AACC), in collaboration with the American Diabetes Association® (ADA), has released evidence-based guidelines to help diagnose and manage patients with diabetes using the latest laboratory-analysis tools. The guidelines replace previous versions published in 2002 and 2011.

The new document features extensive updates on continuous glucose monitoring and more precise recommendations for measuring glucose and hemoglobin A1c. Written by a cross-disciplinary team of medical experts, the guidelines provide specific, actionable advice that will enhance collaboration among healthcare professionals and improve care for millions of people.

Among the most significant additions to the 2023 document is its recommendations around continuous glucose monitoring (CGM), where a patient’s blood glucose is measured every 5-15 minutes. The team recommends using real-time CGM in conjunction with insulin as a tool in certain teens and adults with type 1 diabetes. This recommendation applies to patients with type 1 diabetes who are not meeting their blood sugar (glycemic) targets, are unaware of when their blood sugar is low, and/or are prone to low blood sugar. CGM is not used frequently for patients with type 2 diabetes, however, the guidelines suggest that providers consider CGM for type 2 patients using insulin who are not meeting their glycemic targets.

The new document also recommends that healthcare workers use blood-collection tubes that contain a citrate buffer to minimize the breakdown of glucose after blood samples are taken. This is important because such glucose breakdown compromises the accuracy of measurements.

In addition, the team provides new guidance for standardizing measurements of insulin and C-peptide, a marker that helps distinguish between type 1 and type 2 diabetes. Further updates cover autoimmune and genetic markers for type 1 diabetes, including a promising analysis of gene mutations that can detect rare forms of neonatal diabetes.

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Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Point-of-CarePoint-of-Care Testing (POCT) or Near Patient Testing (NPT) products are available for urine, blood and other clinical chemistry analyses. POCT includes: blood glucose testing, blood gas and electrolytes analysis, rapid coagulation testing (PT / INR), rapid cardiac markers diagnostics, drugs of abuse screening, urine strips testing, pregnancy testing, fecal occult blood analysis, food pathogens screening, hemoglobin diagnostics, infectious disease testing and cholesterol screening.Clinical ChemistryBiochemistry (or clinical chemistry) involves the analysis of bodily fluids using chemical tests. Techniques used include HPLC, chromatography, spectroscopy, mass spectrometry, immunochemical, electrophoresis, turbidometric / spectrophotometric assay, MRI and ISE analysis. Tests are often carried out on plasma or serum but urine (urinalysis) and fecal specimens are also processed.DiabetesDiabetes is a metabolic disorder characterized by high blood sugar levels, either due to insufficient insulin production or resistance to its effects. Ongoing diabetes innovation focuses on developing better diagnostic tools, treatments, and preventive measures. Browse our peer-reviewed product directory to find the best diabetes diagnostic tools, compare products, check reviews, and get pricing directly from manufacturers.Laboratory ManagementLaboratory management involves overseeing the operations of a lab, ensuring compliance with safety regulations, optimizing workflows, and maintaining equipment. Efficient lab management is key to ensuring accurate results and minimizing downtime. Technologies like laboratory information management systems (LIMS) and automated lab equipment are helping labs streamline operations. Browse our peer-reviewed product directory to find the best laboratory management tools, compare products, read reviews, and get pricing directly from manufacturers.AACCThe American Association for Clinical Chemistry (AACC) Annual Meeting and Clinical Lab Expo is the largest meeting for clinical laboratory professionals in the world. This year's meeting is being held in Atlanta, USA, July 26th-30th, 2015.ADLM
AACC releases comprehensive guidelines on diabetes testing