A powerful, straightforward method for determining sample purity

18 Jun 2007

Product news

A new technical paper is available from Exeter Analytical that demonstrates how CHN microanalysis offers a powerful and straightforward method for determining sample purity by providing a precise and accurate analysis of percentage carbon, hydrogen and nitrogen content.

Laboratories tasked with characterising samples today have a wide range of analytical techniques at their disposal. However no one analytical technique can provide the full information to characterise a sample. A key aspect of sample characterisation is often determination of sample purity.

The paper examines a range of sample types that pose problems for determining sample purity using popular analytical techniques such as Mass Spectrometry (MS) and Nuclear Magnetic Resonance (NMR) Spectroscopy. Using example analyses from industrial and academic customers the authors demonstrate how, with modern horizontal furnace CHN microanalysis instrumentation, precise and accurate results without constant system optimisation can be obtained for a wide range of samples types from organic compounds, through organometallic species to proteins and peptides.

The report concludes that a horizontal furnace design CHN microanalyser, such as the Exeter Analytical Model CE440, is a powerful complimentary tool to MS and NMR for analysts seeking to reliably characterise samples.

A copy of the technical paper 'CHN microanalysis - a technique for the 21st century?' can be downloaded from the article webpage.

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Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. NMR and EPR SpectroscopyNuclear magnetic resonance (NMR) spectroscopy is used to resolve the local chemical environment of atomic nuclei with spin, revealing information on molecular structure, dynamic processes and chemical reactions of organic molecules, from proteins to synthetics. Electron paramagnetic resonance (EPR) also known as electron spin resonance (ESR) spectroscopy is used to detect and quantify paramagnetic species in a sample, including free radicals as transition metal ions. By immersing the sample in a strong magnetic field, both NMR and EPR spectrometers probe the sample with either radio waves or microwaves respectively. A range of benchtop, solid-state and time domain NMR spectrometers & EPR spectrometers are available, as well as NMR tubes, NMR solvents, software, coils, and magnets. Find the best NMR & EPR equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.
A powerful, straightforward method for determining sample purity