8 top trends in multiplexing: Could this technology transform your lab?

Discover the latest research applications using multiplex technology to maximize sample use, while saving time and money

3 May 2020
Charlie Carter
Life Sciences Editor

Editorial article

Upgrade your single-cell data with higher-plexing

Explore a series of case studies illustrating the research capabilities of high-plexing assays in this free application eBook. Plus, receive top tips on how to achieve accurate, reliable results for virtually any target species, tissue, or gene with RNAscope™ technology from Advanced Cell Diagnostics.

The study of memory mechanisms to identify new therapeutic targets for PTSD

Watch this video interview with Dr. Mark Cembrowski, Assistant Professor at the University of British Columbia, and Kaitlin Sullivan, an MSc student in the Cembrowski Lab, to find out how single-cell RNA sequencing is being used to identify potential targets to treat fear memory disorders.

How to buy: Multiplex assay technology

Multiplexing is the process of measuring multiple analytes simultaneously from a single sample in a single experimental run. Download our free how-to-buy eBook and receive a step-by-step guide to numerous multiplex assay technologies, ranging from bead-based assays to solid-phase microarrays, so you can make an informed decision on the best choice for your laboratory.

Michael Surace, AstraZeneca

Design, optimize, and validate your multiplex immunofluorescence panels

Multiplex immunofluorescence (mIF) combines the spatial information from immunohistochemistry (IHC) with multimarker phenotypes. Watch this on-demand, expert webinar on the recent advances in mIF technology and the key considerations for producing a high-performing panel that avoids undesirable interactions between the detection of the targets and neighboring visible light spectra.

Nano-injection technology for improved CRISPR delivery

With traditional delivery methods, the success of CRISPR-Cas-mediated gene editing is often less than optimal due to poor cell viability and low transfection efficiency rates. In this expert interview, discover the novel nano-injection technology that promises to enable significantly enhanced gene editing rates, optimized on/off-target effects and easy multiplexing of CRISPR mutations.

The importance of the cellular microenvironment for effective drug development

In this SelectScience article, we speak with Dr. Nathalie Maubon, founder of HCS Pharma, a biotechnological start-up focused on in vitro preclinical research and development. With a specialization in automated cellular imaging, HCS Pharma hopes to use high-content analysis and high-content screening to obtain and select more effective treatments against complex diseases.

Multiplexed screening of drug-induced mitochondrial dysfunction and cytotoxicity

Download this free application note that assesses the feasibility of combining cytotoxicity and mitochondrial function measurements into a single, multiplexed ‘mix-and-measure’ assay, thereby simplifying screening workflows.

Maximize throughput with multichannel liquid chromatography

With traditional single-channel LC-MS systems, the mass spectrometer lies idle for significant periods of time as the samples are processed sequentially, leading to reduced efficiency and increased time and cost per sample. Download this application guide to perform fast, efficient LC-MS/MS clinical analysis using multichannel LC and online sample technologies.

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ImmunologyImmunological techniques measure and characterize immune responses. Immunology kits and analysis systems often use techniques such as ELISA, radioimmunoassay (RIA) and immunodiffusion assays, Immunohistochemistry, and flow cytometry. Immunologists use equipment such as flow Cytometers, plate readers, plate washers and fluorescent microscopes.Cell-Based AssaysCell-based assays are used to monitor the presence, quantity and activities of a desired cellular analyte including drug molecules or biomarkers. This can reveal information on cell health (apoptosis, cytotoxicity, viability and proliferation assays), cell metabolism, cell migration and cell signaling mechanisms. Find the best cell-based assay products, kits and equipment with our peer reviewed product directory: compare products, check customer reviews and receiving pricing direct from manufacturers.In Vivo Imaging Systems<i>In vivo</i> imaging systems, including pre-clinical imaging systems and medical imaging systems are used to non-invasively visualize and capture images of live animals and plants. Monitor the natural processes or diseases of your subjects using small-animal pre-clinical imaging systems, including single photon positron emission tomography (SPECT), positron emission tomography (PET), computed tomography (micro-CT), magnetic resonance imaging (MRI), X-ray radiography, ultrasound, fluorescence and bioluminescence imagers. Multimodal systems and software solutions are also available for correlative analysis of organ, tissue, cell, or molecular-level processes. Find the best in vivo imaging products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.ImmunohistochemistryImmunohistochemistry (IHC) is a technique used to detect specific proteins in tissue samples by using antibodies that bind to target antigens. IHC is widely applied in pathology, immunology, hematology and cancer diagnostics. Explore IHC tools in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.High Content ImagingHigh content imaging is a method combining two or more fluorescent microscopy experiments to identify substances that alter a cell’s phenotype in a desired manner. The process is adapted to multi-well plates and both the image acquisition and analysis are automated.In Vitro DiagnosticsIn vitro diagnostics (IVD) involve testing samples outside the body, typically in a laboratory, to diagnose diseases or conditions. IVD technologies include blood tests, molecular assays, and other bodily fluid tests, enabling accurate diagnosis and monitoring of diseases. These tests are essential for guiding treatment decisions in clinical settings. Browse our peer-reviewed product directory to find the best IVD solutions; compare products, check reviews, and get pricing directly from manufacturers.CRISPRCRISPR technology enables precise editing of genes, allowing scientists to modify DNA at specific locations. This revolutionary tool is used in genetic research, drug development, and gene therapy. CRISPR has applications in agriculture, disease treatment, and creating genetically modified organisms (GMOs). Explore CRISPR solutions in our peer-reviewed product directory; compare products, check reviews, and get pricing directly from manufacturers.MultiplexingMultiplexing refers to the ability to measure multiple targets or analytes simultaneously in a single experiment. This technique is valuable for high-throughput screening, diagnostics, and complex assays, as it increases efficiency and data quality. Browse our peer-reviewed product directory to find the best multiplexing products, compare tools, check reviews, and get pricing directly from manufacturers.