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5 expert webinars you won't want to miss

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Explore topics from LC-MS for oligos, peptides, glycans, and large molecule characterization to 3D cell culture for anticancer therapies

3 May 2021
Edward Carter
Publishing / Media

Expert insights

SelectScience® hosts dozens of informative and insightful free webinars for scientists every month, featuring world-class speakers at the very forefront of their respective fields. In this regular weekly feature, we highlight the events you won't want to miss over the next week or so, as well as some of our top on-demand webinars. Register now to save your spot and hear from experts as they discuss the latest research and technologies in their fields, from enhancing LC-MS analysis of oligos, peptides, glycans, and large molecule characterization to 3D cell culture for anticancer drug therapies and spectroscopy for drug discovery and development.

 

RAMAN: Spectroscopy tools in drug discovery and development

Dr. Julia Griffen, Product Manager, and Darren Robey, Product Manager of IR Imaging at Agilent Technologies, will discuss high-resolution surface mapping using laser direct infrared (LDIR), a surface mapping technique that uses a state-of-the-art quantum cascade laser to create exceptionally high-resolution images with unprecedented speed.

Tuesday, May 4, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Register here

PROTEIN BIOLOGY: Enhancing LC-MS analysis of oligos, peptides, and glycans using hybrid surface technology

Jennifer Nguyen, Principal Scientist, Jacob Kellett, Associate Scientist, and Dr. Xiaoxiao Liu, Senior Scientist at Waters Corp, will describe the benefits of the ACQUITY PREMIER Solution with MaxPeak High Performance Surface Technology in mitigating problematic metal interactions.

Friday, May 7, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Register here

OLIGOS: Bioanalytical method development for oligonucleotides: Overcoming the analytical challenges

Mary Trudeau, principal applications scientist at Waters Corporation, will outline the key challenges in method development for oligonucleotides and solutions to address them. Trudeau will illustrate these challenges and solutions through a number of examples, including various oligodeoxythymidines and the antisense oligonucleotide therapy, GEM91, and place particular emphasis on how to achieve maximum resource utilization and improve selectivity and sensitivity in oligonucleotide bioanalysis using LC-MS/MS.

Monday, May 10, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Register here

3D CELL CULTURE: Multimodal analysis of anticancer drug testing in tumor-specific 3D cell culture models

Dr. Julia Kirshner, Founder and CEO of zPREDICTA, will discuss the advantages of using 3D culture models over the traditional methods, with particular emphasis on the importance of tumor microenvironment and tissue-relevant extracellular matrix (ECM) in obtaining accurate drug response data.

Wednesday, May 12, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Register here

MASS SPECTROMETRY: Large molecules get SLIM: High-Resolution Ion Mobility for simplifying complex large molecule characterization

Dr. Jim Arndt, from MOBILion, and Dr. Jeffrey Agar, Associate Professor at Barnett Institute Northeastern University, will discuss the benefits of HRIM-MS for enhancing structural characterization of large molecule therapeutics, while increasing throughput and reducing reliance on LC-based methods.

Friday, May 14, at 16:00 BST / 17:00 CEST / 11:00 EDT / 08:00 PDT

Register here

Catch up on these 5 on-demand webinars and virtual events

  • How to minimize the risk of food fraud due to coronavirus: Dr. Bert Popping, Managing Director at FOCOS, explores the recent developments in the molecular methods field and put these methods in the context of standardization and existing public and private law. Watch here>>
  • Off-load gene therapy and vaccine buffer exchange to Big Tuna: Joe Barco, from Unchained Labs, discusses new methods tailored to each gene therapy vector type, and how these finicky samples can now be exchanged and concentrated in a higher-throughput manner with Big Tuna – offering faster and more consistent sample exchange without compromising sample integrity or recovery. Watch here>>
  • Raman spectroscopy: A practical solution to today's characterization challenges: Dr. Adam Holland and Dr. Steven Booth explore the advances in hardware and software that have made today’s instrumentation accessible to non-Raman experts.Watch here>>
  • Discovery and development of antibody therapies for COVID-19: Find out how high-throughput epitope binning and mapping using label-free biolayer interferometry (BLI) detection and advanced flow cytometry systems has enabled the development of an antibody cocktail that can reduce the risk of drug resistance. Watch here>>
  • Beyond the basics of image analysis: Image registration and spatial infiltration analysis in HALO: Andreas Theodosi, research scientist, and James Clay, image analysis manager, take a look at the application serial section registration of pan-cytokeratin, estrogen receptor, progesterone receptor, and CD8-stained serial sections of human breast carcinoma samples. Watch here>>

Have a conflicting schedule? Don't worry all SelectScience webinars are made available on demand, find out more here>>

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LC-MSLC-MS (liquid chromatography-mass spectrometry) systems and equipment are used for separation and quantitative analysis of complex mixtures, combining liquid chromatography and mass spectrometry. Quantify proteins, contaminants, pesticides or screen for drug metabolites with a high level of sensitivity. LC-MS systems and equipment include reverse phase, normal phase and specialized columns integrated with various MS detectors such as time-of-flight (TOF), quadrupole, orbitrap or ion trap mass analyzers. LC-MS/MS instruments equipped with a qTOF or triple quadrupole analyzer give greater sensitivity and resolving power to your analysis. Find the best LC-MS equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Genome AnalysisGenomics, the study of genomes, includes functional genomics, evolutionary genomics and comparative genomics. There are many genomic technologies such as DNA sequencing of whole genomes, computational biology and bioinformatics. DNA and nucleic acids must be isolated and concentrated from cells for analysis with kits, automated analyzers and software. Other useful technologies for studying genomics include PCR, microarrays and electrophoresis.Cellular PathologyCellular Pathology deals with the microscopic analysis of tissue samples and cells. Sample preparation and processing includes fixation, staining, sectioning and slide mounting, using equipment such microtomes and cryostats. In choosing immunohistochemistry and immunocytochemistry kits, consider chromogens, staining method, antibodies, microscopes and imaging.Gene Expression and Molecular CloningMolecular cloning is a set of techniques that utilizes vectors to transfer recombinant DNA into host cells and is an essential tool for investigating the expression of genes and proteins in bacterial or mammalian cells. A variety of vectors optimized for gene cloning and expression in a range of host organisms are available, alongside competent cells for genetic replication. Here, you can explore a range of molecular tools, high-quality genomic and cDNA libraries, premade clones, transformation and transfection reagents and mutagenesis or gene expression detection assays and expression arrays. Find the best gene expression and molecular cloning products in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Cell / Tissue CultureCell culture or tissue culture is used to study the biology of cells or tissues and to isolate cellular products in an environment which can be manipulated and well defined. Accurately control your culture environment with bioreactors or culture incubators, bind your cells to a surface or together with an extracellular matrix. Distinguish cell types with differential media or proliferate cells with certain characteristics using selective media. Enrich your media with supplements such as growth factors, sera and vitamins. Find the best cell and tissue culture products, kits and equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.OligonucleotidesOligonucleotides are small nucleic acid polymers, usually less than 20 bases in length. Oligonucleotides can be made via enzymatic cleavage or more commonly by chemical synthesis with polymerases. Their use includes FISH, southern blots, microarrays and as primers in PCR. High fidelity synthesis kits and detection systems are available for easy production and detection, respectively.GlycansPeptidesPeptides are short chains of amino acids that play key roles in biological processes, including signaling, immune responses, and enzyme regulation. Peptide research is critical in drug discovery, diagnostics, and vaccine development. Browse our peer-reviewed product directory to find the best peptides and peptide-related products, compare options, check reviews, and get pricing directly from manufacturers.SpectroscopySpectroscopy is a technique that analyzes the interaction of light with matter to study molecular properties, concentrations, and structural information. Widely used in chemical, pharmaceutical, and environmental analysis, spectroscopy offers insights into molecular composition and helps identify unknown compounds. It plays a key role in quality control, research, and diagnostics. Browse our peer-reviewed product directory to compare spectroscopy tools, read reviews, and get prices directly from manufacturers.LC-MSLiquid Chromatography-Mass Spectrometry (LCMS) is a powerful analytical technique that combines the separation power of liquid chromatography with the detection capabilities of mass spectrometry. It is widely used for qualitative and quantitative analysis of complex mixtures in pharmaceuticals, proteomics, and environmental studies. Browse our peer-reviewed product directory to find the best LCMS systems, compare products, check reviews, and get pricing directly from manufacturers.Cancer ResearchAlthough cancer is often referred to as a single condition, it actually consists of more than 100 different diseases. Microscopy, mass spectrometry, high throughput sequencing and flow cytometry are some of the most common techniques employed in cancer research labs.

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