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2D Ion Chromatography System for Analyzing Small Organic Acids in a High Ionic Strength Matrix

Thermo Fisher Scientific
6 Aug 2012
Tesni Perry
Administrator / Office Personnel

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Thermo Fisher Scientific is pleased to announce a two-dimensional ion chromatography (IC) system that allows trace levels of small organic acids (C1–5) to be analyzed in a high-ionic-strength matrix.

Application Note 1000: Direct Determination of Small Organic Acids in Sea Water by IC-MS demonstrates low-level sensitivity for detection while maintaining method ruggedness for a complex analysis. This method combines separation by hydroxide-selective anion-exchange columns with the sensitivity and selectivity of a single quadrupole mass spectrometer. This approach provides accurate identification and quantification of the analytes. No special sample preparation is required and the results show good precision and reproducibility.

Short-chain organic acids play important roles in adjusting the pH value of the marine environment. In light of the significant growth in aquaculture for farmed fish and shellfish, several feed additives—including acidifiers consisting of organic acids and their salts—may provide promising alternatives to the use of in-feed antibiotics in aquaculture. Analysis for organic acids in aqueous matrices allows fisheries to monitor the water environment and control its impact on the health of the fish. Analysis by IC-mass spectrometry (MS) provides a faster, more direct approach that does not require sample pretreatment.

The application note is available on the Thermo Fisher Scientific Dionex website, under the ‘Documents’ tab.

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Gas ChromatographyGas chromatography (GC) is an analytical technique used to separate and quantitate mixtures of small and volatile compounds. Gas chromatographs or GC systems include components such as GC columns, detectors, pumps and autosamplers. Choose from packed or capillary GC columns, flame ionization (FID), photoionization (PID) electron capture detectors and selective or non-selective detectors. Find the best gas chromatographs in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Ion ChromatographyIon chromatography, also known as ion exchange chromatography, is a high-performance liquid chromatographic technique used for the separation and identification of ions or polar molecules in a sample, including proteins, nucleotides and amino acids. Equipment includes ion exchange columns, ion exclusion columns, ion chromatography systems, pumps, and detectors. Find the best ion chromatography equipment in our peer-reviewed product directory: compare products, check customer reviews and receive pricing direct from manufacturers.Mass SpectrometryMass spectrometry (MS) is a powerful analytical technique used to identify and quantify molecules based on the mass-to-charge ratio of gas-phase ions. It provides detailed information about the structure, composition, and properties of compounds and is widely used across fields such as environmental monitoring, materials science, drug discovery and development, food and beverage testing, and wider chemical research. Key MS techniques include tandem mass spectrometry (MS/MS), liquid chromatography–mass spectrometry (LS-MS) and inductively coupled plasma (ICP-MS). Choosing from these wide range of techniques and technologies can be a daunting task, so keep up to date with scientific applications, performance expectations, and customer reviews here all in one place. Visit our product directory to receive quotes direct from the manufacturer. Environmental Monitoring and TestingEnvironmental monitoring and testing uses handheld portable analyzers, kits, spectrometers or chromatography systems for air, water, soil, food and other sample testing. Useful features of analyzers such as BOD and COD include portability, easy calibration, automation and sensitivity.  Environmental test kits for pH, water, moisture, etc, should be accurate, sensitive, reliable, fast and easy to use.pH and Conductivity MetersIon and pH meters, used for electrochemical techniques and measurements, measure the concentration of specific ions using electrodes (probes) and a meter. Features of ph and ion meters to consider include temperature compensation, auto-calibration, adjustable resolution, measurable range and accuracy. Meters can be handheld, portable, benchtop and modular.Water AnalysisAnalytical methods used to test the purity of drinking water include determining the level of contaminants abides to the level set by the Environmental Protection Agency (EPA).

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2D Ion Chromatography System for Analyzing Small Organic Acids in a High Ionic Strength Matrix